Prognostic factor identification by screening changes in differentially expressed genes in oral squamous cell carcinoma.

Boris SchminkeOrr ShomroniGabriela SalinasFelix BremmerPhilipp KauffmannHenning SchliephakeFelix OyelamiMichal A RahatPhillipp Brockmeyer

Published in: Oral diseases (2021)

We identified changes in differentially expressed genes during OSCC progression in vitro and translated the impact of the most deregulated genes on patient prognosis. Stearoyl-CoA desaturase-1 and sclerostin acted as independent prognostic factors in OSCC and could also be interesting candidates for new cancer targeted therapeutic approaches.

Keyphrases

prognostic factors
bioinformatics analysis
genome wide
genome wide identification
papillary thyroid
case report
dna methylation
cancer therapy
squamous cell carcinoma
drug delivery