Histopathological validation of semi-automated myocardial scar quantification techniques for dark-blood late gadolinium enhancement magnetic resonance imaging.
Hedwig M J M NiesSuzanne GommersGeertruida P BijvoetLuuk I B HeckmanFrits W PrinzenGaston VogelCaroline M Van De HeyningAmedeo ChiribiriJoachim E WildbergerCasper MihlRobert J HoltackersPublished in: European heart journal. Cardiovascular Imaging (2022)
The signal threshold vs. reference mean method with a threshold of 5 SDs demonstrated the most accurate semi-automated quantification of infarcted myocardium, without significant bias compared to histopathology, for both conventional bright-blood and novel dark-blood LGE.