The Inhibition of Wnt Signaling Attenuates RANKL-induced Osteoclastogenic Macrophage Activation.

Dai YamanouchiKimihiro Igari

Published in: Vascular biology (Bristol, England) (2023)

The inhibition of Wnt signaling pathway via ICG-001 suppressed osteoclastogenic macrophage activation. Our previous studies have shown the importance of osteoclastogenic macrophage activation in AAA. Further research to examine the therapeutic potential of ICG-001 on AAA is warranted.

Keyphrases

adipose tissue
signaling pathway
fluorescence imaging
stem cells
cell proliferation
pi k akt
high glucose
induced apoptosis
endothelial cells
photodynamic therapy