A genome-wide association study on liver enzymes in Korean population.

Ji Yeon SeoJong-Eun LeeGoh-Eun ChungEunsoon ShinMin-Sun KwakJong In YangJeong Yoon Yim

Published in: PloS one (2020)

We demonstrated that ABO, GGT1 and UGT1A family were associated with ALP, GGT and BIL, respectively in Korean population. These findings differ from reported results in GWAS in European populations in terms of associated genes and locations, suggesting different genetic mechanisms of liver enzyme regulation according to ethnicity.

Keyphrases

genome wide association study
genome wide
copy number
gene expression
transcription factor
genetic diversity