Lean in one way, in obesity another: effects of moderate exercise in brown adipose tissue of early overfed male Wistar rats.
Douglas Lopes AlmeidaVeridiana Mota MoreiraLucas Eduardo CardosoMarcos Divino Ferreira JuniorAudrei PavaneloTatiane Aparecida RibeiroClaudinéia Conationi da Silva FrancoLaize Perón TófoloMaria Natália Chimirri PeresMaiara Vanusa Guedes RibeiroAnna Rebeka Oliveira FerreiraRodrigo Mello GomesRosiane Aparecida MirandaIsis Hara TrevenzoliJames Andrew ArmitageKesia Palma-RigoPaulo Cesar de Freitas MathiasPublished in: International journal of obesity (2005) (2021)
Moderate exercise chronically increased BAT thermogenesis in both, NL and SL groups. In NL-Exe by increasing Sympathetic activity, and in SL-Exe by a combination of increased β3-AR and UCP1 content with morphologic remodeling of BAT. Chronically increasing BAT thermogenesis in obese subjects may lead to higher overall energy expenditure, favoring the reduction of obesity and related comorbidities.