Serum IGF-1 is associated with cognitive functions in early, drug-naïve Parkinson's disease.

Marina PicilloRosario PivonelloGabriella SantangeloClaudia PivonelloRiccardo SavastanoRenata AuriemmaMarianna AmboniSara ScannapiecoAngela PierroAnnamaria ColaoPaolo BaroneMaria Teresa Pellecchia

Published in: PloS one (2017)

Lower serum IGF-1 levels are associated to poor performances in cognitive tasks assessing executive function, attention and verbal memory in a large cohort of early PD patients. Follow-up studies are warranted to assess if IGF-1 is related to the development of dementia in PD.

Keyphrases

working memory
end stage renal disease
pi k akt
ejection fraction
binding protein
newly diagnosed
chronic kidney disease
growth hormone
peritoneal dialysis
mild cognitive impairment
emergency department
patient reported outcomes
case control
electronic health record