Colorimetric and Fluorimetric DNA Detection with a Hydroxystyryl-Quinolizinium Photoacid and Its Application for Cell Imaging.
Avijit Kumar DasSergey I DruzhininHeiko IhmelsMareike MüllerHolger SchönherrPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2019)
The combination of styryl dye properties with the acidity and strong photoacidity of the 2,2'-[(1''-hydroxy-4''-methyl-(E)-2'',6''-phenylene)]-bisquinolizinium enables the detection of DNA by distinct absorption and emission color changes and the fluorimetric detection of DNA in cells with epifluorescence and confocal fluorescence microscopy.
Keyphrases
- single molecule
- label free
- circulating tumor
- loop mediated isothermal amplification
- cell free
- high resolution
- real time pcr
- induced apoptosis
- gold nanoparticles
- single cell
- optical coherence tomography
- cell cycle arrest
- cell therapy
- oxidative stress
- circulating tumor cells
- nitric oxide
- cell death
- highly efficient
- photodynamic therapy
- signaling pathway
- raman spectroscopy
- energy transfer