Human bone marrow contains high levels of extracellular vesicles with a tissue-specific subtype distribution.

Andreas RankRienk NieuwlandAnton KöhlerCordula FranzJohanna WaidhauserBettina Toth

Published in: PloS one (2018)

Taken together, we describe EV numbers and their subtype distribution in the BM compartment for the first time. The tissue specific EV distribution reflects BM cell composition and favours the idea of a BM-PB barrier existing not only for cells, but also for EV.

Keyphrases

bone marrow
induced apoptosis
endothelial cells
mesenchymal stem cells
single cell
cell cycle arrest
cell therapy
risk assessment
cell death
endoplasmic reticulum stress