Locked-in syndrome after central pontine myelinolysis, an outstanding outcome of two patients.
Maïlys ChabertCorentin DauleacMaude Beaudoin-GobertMélaine De-QuelenSophie CianciaTimothée JacquessonSimon BertrandEmmanuel VivierDonatien De-MarignanJulien JungNathalie Andre-ObadiaFlorent GobertFrançois CottonJacques LuautéPublished in: Annals of clinical and translational neurology (2024)
The possibility of a near-complete functional recovery at 12 months is important to consider given the ethical issues at stake and the discussions about limiting care that may take place initially. It seems to be the consequence of reversible myelin damage combined with partially preserved neurons. Development of collateral pathways or resolution of conduction block may explain this recovery. MRI comprising DTI and tractography could play a key role in the prognosis of motor recovery.
Keyphrases
- end stage renal disease
- white matter
- newly diagnosed
- ejection fraction
- healthcare
- chronic kidney disease
- magnetic resonance imaging
- prognostic factors
- palliative care
- oxidative stress
- peritoneal dialysis
- computed tomography
- contrast enhanced
- quality improvement
- multiple sclerosis
- single molecule
- pain management
- spinal cord injury
- patient reported