Left atrial remodeling in mitral regurgitation: A combined experimental-computational study.

Sjoerd BouwmeesterTim van LoonMeike PloegThomas P MastNienke J VerzaalLars B van MiddendorpMarc StrikFrans A van NieuwenhovenLukas R DekkerFrits W PrinzenJoost LumensPatrick Houthuizen

Published in: PloS one (2022)

MR augmented LA strain acutely to supranormal values without significant LA dilation. However, over time, LA strain gradually decreases (pseudornormal and decompensated) with LA dilation. Histology and computer simulations indicated a correlation to a varying degree of LA eccentric remodeling and fibrosis.

Keyphrases

left atrial
heart failure
atrial fibrillation
mitral valve
left ventricular
magnetic resonance
computed tomography
molecular dynamics
catheter ablation
machine learning
ejection fraction
virtual reality
monte carlo