Interleukin-10 and tumour necrosis factor alpha promoter region polymorphisms and susceptibility to urogenital schistosomiasis in young Zimbabwean children living in Schistosoma haematobium endemic regions.

Amos Marume Arthur Vengesai Jaclyn Kelly Mann Takafira Mduluza

Published in: Southern African journal of infectious diseases (2020)

Interleukin-10 -1082 G/A, IL-10 -819 C/T and TNF-α -308 G/A SNPs were not significantly associated with susceptibility to S. haematobium infection. The prevalence of schistosomiasis is still in the moderate range and is similar in boys and girls.

Keyphrases

dna methylation
rheumatoid arthritis
young adults
risk factors
genome wide
gene expression
transcription factor
high intensity