Does Colectomy Improve Type 2 Diabetes?
Suriya PunchaiRickesha L WilsonKatherine M MeisterZubaidah Nor HanipahRoman VangoitsenhovenPhilip R SchauerScott R SteeleTracy L HullAli AminianPublished in: Obesity surgery (2021)
Gastrectomy and gastric bypass improve type 2 diabetes (T2DM), potentially through alterations in intestinal hormones and the microbiome. The aim of this study was to analyze whether colorectal resections result in improvement of T2DM. A total of 171 patients with T2DM who underwent colectomy for benign diseases were studied with a median postoperative follow-up of 3 years (interquartile range [IQR] 1-5). The median BMI and glycated hemoglobin (HbA1c) at baseline and post-colectomy were 30.3 kg/m2 (IQR 26.6-34.6) versus 30.4 kg/m2 (IQR 26.2-35) (p = 0.1), and 6.7% (IQR 6.2-7.5) versus 6.5% (IQR 6.5-7.1) (p = 0.5), respectively. The proportion of patients taking diabetes medications at baseline versus post-colectomy did not differ significantly. Changes in BMI, HbA1c, and status of diabetes medications were not statistically different between the subtypes of colorectal resection. Our experience suggests that colectomy for benign colorectal diseases is not associated with long-term changes in body weight or glycemic control.
Keyphrases
- glycemic control
- type diabetes
- weight loss
- blood glucose
- gastric bypass
- body weight
- insulin resistance
- body mass index
- end stage renal disease
- roux en y gastric bypass
- bariatric surgery
- ejection fraction
- cardiovascular disease
- newly diagnosed
- patients undergoing
- weight gain
- obese patients
- peritoneal dialysis
- adipose tissue
- metabolic syndrome
- patient reported outcomes