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Sensitivity and predictive value of dysentery in diagnosing shigellosis among under five children in Zambia.

Sam MitiObvious N ChilyabanyamaCaroline Cleopatra ChisengaMwelwa ChibuyeSamuel BosomprahChisenga MumbaSalome ChitondoSeter SiziyaDani CohenRoma ChilengiMichelo Simuyandi
Published in: PloS one (2023)
Use of clinical dysentery as a screening symptom for Shigella infection in children under five presenting with moderate to severe diarrhea has low sensitivity and low positive predictive value respectively. Clinical dysentery as a screening symptom for Shigella contributes to gross under diagnosis and reporting of Shigella infection among under five children in Zambia. Further research is required to better inform practice on more accurate methods or tools to use in support of routine diagnosis, particularly in low middle-income settings where laboratory diagnosis remains a challenge.
Keyphrases
  • young adults
  • healthcare
  • primary care
  • emergency department
  • high resolution
  • case report
  • clinical practice
  • patient reported
  • irritable bowel syndrome
  • drug induced