MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis.

P MöhnleS HirschbergerL C HinskeJ BriegelM HübnerS WeisG DimopoulosM BauerE J Giamarellos-BourboulisSimone Kreth

Published in: Molecular medicine (Cambridge, Mass.) (2018)

These findings suggest miR-143 and miR-150 as promising markers for detection of T-cell immunosuppression in whole blood and may help to develop new approaches for miRNA-based diagnostic in sepsis.

Keyphrases

cell proliferation
long non coding rna
acute kidney injury
intensive care unit
long noncoding rna
loop mediated isothermal amplification
septic shock
label free