Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization.

Xin WangChun-Gu HongRan DuanZhi-Lin PangMin-Na ZhangHui Xie Zheng-Zhao Liu

Published in: Spinal cord (2024)

OM-MSCs reduced the level of inflammation in the spinal cord tissue, protected neurons, and repaired spinal cord injury by regulating the M1/M2 polarization of microglia.

Keyphrases

spinal cord
spinal cord injury
neuropathic pain
inflammatory response
oxidative stress
mesenchymal stem cells
bone marrow
lipopolysaccharide induced
umbilical cord
lps induced
cell therapy
stem cells