Interim-analysis of the COSA (COVID-19 patients treated with the Seraph® 100 Microbind® Affinity filter) registry.
Julius J SchmidtDan Nicolae BorchinaMariet van T KloosterKhalida Bulhan-SokiReuben OkiomaLarissa HerbstDiego Sandoval RodríguezVedran PremužićStefan BüttnerBirgit BaderWojciech SerednickiEwa ZasadaMichael SchmitzRalf A QuabachMaria HrinchevaThomas FühnerJan T KielsteinPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021)
The treatment of COVID-19 patients with Seraph®100 is well tolerated and the circuit failure rate was lower than previously reported for KRT in COVID-19 patients. Mortality corelated with late initiation of Seraph treatment after ICU admission and bacterial superinfection infection. Compared to predicted mortality according to 4C-Score and SOFA Score, mortality of Seraph®100 treated patients reported in the registry was lower.