Left atrial to coronary sinus shunting for treatment of heart failure with mildly reduced or preserved ejection fraction: The ALT FLOW Early Feasibility Study 1-year results.
Marcus A UreyBenjamin HibbertUlrich JordePeter EckmanTrevor SimardMarino LabinazBabak NazerMark WileyBhanu GuptaAndrew SauerHirak ShahPaul SorajjaAndres M PinedaEmil MissovEhtisham MahmudRami KahwashScott LillyAzeem LatibSandhya MurthyNeil FamSantiago GarciaEugene S ChungLiviu KleinRichard ChengBrian A HoustonNicholas S AmorosoLee ChangSameer GafoorSunit-Preet ChaudhryJames HermillerJonathan G SchwartzLillian AldaiaKonstantinos KoulogiannisWilliam A GrayFiras E ZahrPublished in: European journal of heart failure (2024)
In patients with heart failure and LVEF >40%, the APTURE shunt demonstrated an acceptable safety profile with significant sustained improvements in haemodynamic and patient-centred outcomes, underscoring the need for further evaluation of the APTURE shunt in a randomized trial.