Synthesis and Characterization of a New Carbon-11 Labeled Positron Emission Tomography Radiotracer for Orexin 2 Receptors Neuroimaging.
Yanli WangYongle WangYan LiuHua ChengTewodros Mulugeta DagnewYulong XuChangning WangPublished in: Drug design, development and therapy (2024)
R PET probe, despite challenges related to P-gp interaction. This study lays the foundation for further exploration and development of PET probes targeting OXRs, opening avenues for advancing our understanding of OX system functionality within the brain.