Login / Signup

Assessing the linear and non-linear association of HbA1c with cardiovascular disease: a Mendelian randomisation study.

Shan LuoShiu Lun Ryan Au YeungCatherine Mary Schooling
Published in: Diabetologia (2021)
The study suggests a detrimental effect of HbA1c on coronary artery disease in both men and women, and the effect is via a glycaemic characteristic. The shape of the genetic association of HbA1c with these cardiovascular outcomes, in particular coronary artery disease, is likely to be linear.
Keyphrases
  • coronary artery disease
  • cardiovascular disease
  • type diabetes
  • cardiovascular events
  • gene expression
  • coronary artery bypass grafting
  • acute coronary syndrome
  • atrial fibrillation
  • neural network