Genetic mutations in Parkinson's disease: screening of a selected population from North-Eastern Italy.

Giulia BonatoAngelo AntoniniFrancesca PistonesiMarta CampagnoloAndrea GuerraRoberta BiundoManuela PilleriCinzia BertolinLeonardo SalviatiMiryam Carecchio

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2024)

Applying simple clinical criteria for genetic testing allows to increase the probability to identify patients with monogenic PD and better allocate resources. This process is critical to widen the understanding of disease mechanisms and to increase the individuation of patients potentially benefitting from future disease-modifying therapies.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
south africa
current status
gene expression