MOG-IgG1 and co-existence of neuronal autoantibodies.
Amy KunchokEoin Patrick FlanaganKarl N KreckeJohn J ChenJ Alfredo CaceresJustin DominickIan FergusonRevere KinkelJohn C ProbascoMiguel RuvalcabaJonathan D SantoroKurt SieloffJeremy TimothyBrian G WeinshenkerAndrew McKeonSean J PittockPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)
NMDA-R-IgG was the most frequently detected neuronal-IgG to co-exist with MOG-IgG1. MOG-IgG1+/NMDA-R-IgG+ patients most often presented with encephalopathy and seizures. Testing for MOG-IgG1 and NMDA-R-IgG may be warranted in patients with encephalopathy and inflammatory demyelinating syndromes.