Dialysis and a plant-based diet to achieve physiologic urea levels for fetal benefit: Normal pregnancy outcome despite chronic kidney disease and hypertension.
Emma SeedElise GilbertsonPublished in: Obstetric medicine (2022)
Chronic kidney disease significantly increases the risk of adverse maternal and perinatal outcomes. A growing body of evidence suggests that intensive dialysis, achieving physiologic pre-dialysis blood urea, is associated with decreased morbidity. We report a case of a successful pregnancy outcome in a 32-year-old nulliparous woman with stage 4 chronic kidney disease who underwent haemodialysis from 11 to 31 weeks' gestation for fetal benefit and concurrently trialled a plant-based diet. We hypothesise that her dietary changes assisted with urea reduction, enabling her to become dialysis independent. Although we must recognise that such pregnancies remain high risk, as demonstrated both in this case and more recent literature, advances in complex obstetric care and dialysis protocols may now give women with chronic kidney disease a realistic hope of a successful pregnancy.
Keyphrases
- chronic kidney disease
- end stage renal disease
- pregnancy outcomes
- preterm birth
- peritoneal dialysis
- pregnant women
- gestational age
- physical activity
- healthcare
- weight loss
- blood pressure
- birth weight
- palliative care
- systematic review
- preterm infants
- emergency department
- body mass index
- skeletal muscle
- electronic health record
- affordable care act