Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-γ production.

Kei WatariSatoru KonnaiNaoya MaekawaTomohiro OkagawaYasuhiko SuzukiShiro MurataKazuhiko Ohashi

Published in: BMC veterinary research (2019)

Collectively, these results suggest that anti-bovine CTLA-4 antibody can reactivate lymphocyte functions and could be applied for a new therapy against refractory chronic diseases. Further investigation is required for future clinical applications.

Keyphrases

immune response
dendritic cells
current status
peripheral blood
stem cells
bone marrow