Prediction of clinically significant prostate cancer using polygenic risk models in Asians.

Sang Hun Song Eunae Kim Eunjin Woo Eunkyung Kwon Sungroh Yoon Jung Kwon Kim Hakmin Lee Jong Jin Oh Sangchul Lee Sung Kyu Hong Seok-Soo Byun

Published in: Investigative and clinical urology (2022)

Ethnic-specific PRS was developed and validated in Korean males to predict csPCa susceptibility using the largest csPCa sample size in Asia. PRS can be a potential biomarker to predict individual risk. Future multi-ethnic trials are required to further validate our results.

Keyphrases

prostate cancer
radical prostatectomy