A New Complex Design of Fe (II) Isoleucine Dithiocarbamate as a Novel Anticancer and Antivirus against SARSCOV-2 (COVID-19).

Rizal IrfandiRiswandi RiswandiIndah RayaAhyar AhmadAhmad FudholiSulistiani JarreDewi Ratih Tirto SariSanti SantiRonald Ivan WijayaPrihantono Prihantono

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

Cytotoxic test of Fe(II) isoleucine dithiocarbamate showed moderate anticancer activity on MCF-7 cancer cells and showed antiviral activity against SARSCOV-2 by interfering with spike glycoprotein -ACE2 receptors, and inhibiting major proteases and 3Clpro.

Keyphrases

coronavirus disease
sars cov
signaling pathway
metal organic framework
breast cancer cells
high intensity
angiotensin ii
visible light
anti inflammatory