Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans.
Yasuyuki TamaiAkiko EguchiRyuta ShigefukuHiroshi KitamuraMina TempakuRyosuke SugimotoYoshinao KobayashiMotoh IwasaYoshiyuki TakeiHayato NakagawaPublished in: eLife (2022)
This research was supported by JSPS KAKENHI Grant Number 22K08011 and 21H02892, and AMED under Grant Number JP21fk0210090 and JP22fk0210115. Maintaining cirrhotic rats were partially supported by Otsuka Pharmaceutical Company.