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Mitigation of Biotin Interference in Manual and Automated Immunoassays by Preconjugating Biotinylated Antibodies to the Streptavidin Surface as an Alternative to Biotin Depletion.

Heather A NelsonSonia L La'uluJun LuKelly Doyle
Published in: The journal of applied laboratory medicine (2022)
This study demonstrates how assay redesign to include preconjugation of biotinylated capture antibody to streptavidin is an effective alternative to biotin-depletion methods to mitigate biotin interference.
Keyphrases
  • high throughput
  • machine learning
  • climate change
  • deep learning