Clinical value of PET/CT with carbon-11 4DST in the evaluation of malignant and benign lung tumors.

Ryuichi NishiiTsuneo SagaHitomi SudoTakashi TogawaJunpei KuyamaToshiaki TaniTakamasa MaedaMasato KobayashiToshihiko IizasaMasato ShingyojiMakiko ItamiKazunori KawamuraHiroki HashimotoKana YamazakiKentaro TamuraTatsuya Higashi

Published in: Annals of nuclear medicine (2021)

PET/CT with [11C]4DST is as feasible for imaging of lung tumors as [18F]FDG PET/CT. For diagnosing lung tumors, [11C]4DST PET is useful in distinguishing benign nodules from malignancies. [11C]4DST uptake in lung carcinomas is correlated with the proliferative activity of tumors, indicating a promising noninvasive PET imaging of DNA synthesis in malignant lung tumors.

Keyphrases

pet ct
positron emission tomography
pet imaging
high grade
circulating tumor
mass spectrometry