CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands.

Louie N van de LagemaatMaria FlenleyMagnus D LynchDavid GarrickSimon R TomlinsonKamil R KrancDouglas Vernimmen

Published in: Epigenetics & chromatin (2018)

We found that CFP1 is not solely recruited to CpG islands as it was originally defined, but also other regions including non-CpG island promoters and enhancers.

Keyphrases

dna methylation
genome wide
binding protein
gene expression
dna damage
minimally invasive
oxidative stress