Management for Cervical Cancer Patients: A Comparison of the Guidelines from the International Scientific Societies (ESGO-NCCN-ASCO-AIOM-FIGO-BGCS-SEOM-ESMO-JSGO).
Stefano RestainoGiulia PellecchiaMartina ArcieriGiorgio BoganiCristina TalientoPantaleo GrecoLorenza DriulVito ChianteraAlfredo ErcoliFrancesco FanfaniAnna FagottiAndrea CiavattiniGiovanni ScambiaGiuseppe Vizziellinull Gynecologic Oncology GroupPublished in: Cancers (2024)
Cervical cancer continues to have a significant incidence, despite global efforts in HPV vaccination campaigns. Managing this condition involves a diverse team of healthcare professionals. Research in this field is undergoing a period of great revolution in multiple areas, and international guidelines will soon have to adapt to new scientific evidence. This could be true mainly in locally advanced stages, and it could also be true for minimal invasive surgery. This paper aims to summarize and compare the most recent recommendations published by international gynecological oncological societies for patients with cervical cancer. From their comparison, common aspects and disagreements emerged, especially in the diagnostic pathway and follow-up strategies. Several issues that remain to be debated in the literature were addressed and compared, highlighting similarities and differences, from the role of the sentinel lymph node in early stages to that of the adjuvant hysterectomy in locally advanced tumors. On the surgical side, for this last subset of patients, currently, a laparotomic approach is recommended. At the same time, the advent of immunotherapy has just opened up new and promising scenarios in systemic treatment for locally advanced cervical cancer, and international guidelines will soon introduce it into their algorithms.
Keyphrases
- end stage renal disease
- locally advanced
- newly diagnosed
- sentinel lymph node
- rectal cancer
- ejection fraction
- squamous cell carcinoma
- chronic kidney disease
- early stage
- systematic review
- clinical practice
- prognostic factors
- machine learning
- prostate cancer
- minimally invasive
- lymph node
- peritoneal dialysis
- radiation therapy
- climate change
- risk factors
- palliative care
- acute coronary syndrome
- study protocol
- open label
- robot assisted
- patient reported
- combination therapy
- cervical cancer screening