Increased thyroid uptake on 18F-FDG PET/CT is associated with the development of permanent hypothyroidism in stage IV melanoma patients treated with anti-PD-1 antibodies.

Alexandra FrelauXavier Palard-NovelloEva JaliLise BoussemartAlain DupuyPandora JamesAnne DevillersFlorence Le JeuneJulien EdelineThierry LesimpleAntoine Girard

Published in: Cancer immunology, immunotherapy : CII (2020)

SUVmax-Th > 4.1 and Th/B > 2.0 provided perfect diagnostic performances to detect patients that developed PTD. No significant survival difference was found between patients with and without increased thyroid uptake.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
free survival