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QuatCy-I 2 and MHI-I 2 in Photodynamic Therapy.

Sopida ThavornpraditSyed Muhammad UsamaG Kate ParkJason DinhHak Soo ChoiKevin Burgess
Published in: ACS medicinal chemistry letters (2022)
MHI-I 2 ( 1 ) and QuatCy-I 2 ( 2 ) were compared in terms of properties important for early-stage photodynamic therapy preclinical candidates. Thus, experiments were performed to monitor dark cytotoxicities, light/dark cytotoxicity ratios, selectivity of localization in tumors over other organs, and clearance from the plasma.
Keyphrases
  • photodynamic therapy
  • early stage
  • fluorescence imaging
  • cell therapy
  • stem cells
  • mesenchymal stem cells
  • lymph node
  • neoadjuvant chemotherapy