QuatCy-I 2 and MHI-I 2 in Photodynamic Therapy.
Sopida ThavornpraditSyed Muhammad UsamaG Kate ParkJason DinhHak Soo ChoiKevin BurgessPublished in: ACS medicinal chemistry letters (2022)
MHI-I 2 ( 1 ) and QuatCy-I 2 ( 2 ) were compared in terms of properties important for early-stage photodynamic therapy preclinical candidates. Thus, experiments were performed to monitor dark cytotoxicities, light/dark cytotoxicity ratios, selectivity of localization in tumors over other organs, and clearance from the plasma.