Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals.

Anne K BozackSheryl L Rifas-ShimanBrent A CoullAndrea A BaccarelliRobert O WrightChitra AmarasiriwardenaDiane R GoldEmily OkenMarie-France HivertAndres Cardenas

Published in: Clinical epigenetics (2021)

Prenatal metal exposure is associated with DNAm, including DMRs annotated to genes involved in neurodevelopment. Future research is needed to determine if DNAm partially explains the relationship between prenatal metal exposures and health outcomes.

Keyphrases

dna methylation
cord blood
pregnant women
genome wide
gene expression
nk cells
air pollution
current status
risk assessment
climate change
childhood cancer
copy number
heavy metals