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Molecular detection and characterisation of the first Japanese encephalitis virus belonging to genotype IV acquired in Australia.

Chisha SikazweMatthew J NeaveAlice MichiePatrick MiletoJianning WangNatalie CooperAvram LevyAllison ImrieRobert W BairdBart J CurrieDavid SpeersJohn S MackenzieDavid W SmithDavid T Williams
Published in: PLoS neglected tropical diseases (2022)
This case represents the first detection of GIV JEV acquired in Australia, and only the second confirmed fatal human infection with a GIV JEV strain. The close phylogenetic relationship between the Tiwi Islands strain and recent Indonesian viruses is indicative of the origin of this novel GIV lineage, which we estimate has circulated in the region for several years prior to the Tiwi Islands case.
Keyphrases
  • endothelial cells
  • loop mediated isothermal amplification
  • label free
  • disease virus