Identification and characterization of miRNAs during early pregnancy in domestic sheep.

Kisun PokharelJaana PeippoMeng-Hua LiJuha Kantanen

Published in: Animal genetics (2020)

MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA-seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals.

Keyphrases

single cell
endothelial cells
dna damage
transcription factor
electronic health record
rna seq
dna repair
big data
gene expression
dna methylation
machine learning
artificial intelligence
deep learning