Incidence and survival of HNSCC patients living with HIV compared with HIV-negative HNSCC patients.
Katharina HaaseIris PiwonskiCarmen StrombergerNadine ThiemeMax HeilandBenedicta Beck-BroichsitterVeit M HofmannGrzegorz KoflaSteffen SanderUllrich KeilholzKonrad NeumannKatharina StölzelHeidi OlzePhilipp ArensSteffen DommerichAnnekatrin CoordesPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2021)
PLWH were diagnosed with HNSCC at a significantly younger age compared to HIV-negative patients. Taking into account patient age at initial diagnosis, both OS and DFS rates in PLWH are significantly worse compared with a matched control group of HIV-negative patients in advanced tumor stages UICC III/IV. The prognosis (OS) is improved when taking cART treatment, the HIV viral load is undetectable and CD4 count is high.