Body Mass Index and Risk of Diabetic Nephropathy: A Mendelian Randomization Study.

Jingru LuXiaoshuang LiuSong JiangShuyan KanYu AnChunxia ZhengXiang Li Zhi-Hong Liu Guotong Xie

Published in: The Journal of clinical endocrinology and metabolism (2022)

Genetic evidence showed that higher BMI levels were causally associated with increased risk of DN and decreased eGFR levels. Moreover, the increase in BMI level had a greater impact on DN risk in women.

Keyphrases

diabetic nephropathy
body mass index
small cell lung cancer
weight gain
polycystic ovary syndrome
epidermal growth factor receptor
genome wide
type diabetes
gene expression
copy number
adipose tissue
metabolic syndrome
breast cancer risk