Aptamer-Targeted Calcium Phosphosilicate Nanoparticles for Effective Imaging of Pancreatic and Prostate Cancer.

Thomas AbrahamChristopher O McGovernSamuel S LintonZachary WilczynskiJames H Adair Gail L Matters

Published in: International journal of nanomedicine (2021)

Through specific interactions with CCK-B receptors, tumor-targeted nanoparticles containing either ICG or rhodamine WT were well distributed throughout the matrix of both pancreatic and prostate tumors. Tumor-targeted NJs carrying various imaging agents can enhance tumor detection.

Keyphrases

prostate cancer
high resolution
cancer therapy
fluorescence imaging
radical prostatectomy
gold nanoparticles
drug delivery
photodynamic therapy
sensitive detection
mass spectrometry