Detection of mobile genetic elements in multidrug-resistant Klebsiella pneumoniae isolated from different infection sites in Hamadan, west of Iran.
Babak AsghariRezvan GoodarziMilad MohammadiFatemeh NouriMohammad TaheriPublished in: BMC research notes (2021)
Antibiotics susceptibility test was performed on 126 of K. pneumoniae isolates. Also, DNA extraction was done and genes were detected using PCR method. In this study, 67 isolates (53%), carrying both the sulI and sulII genes. Forty-five percent tetracycline-resistant isolates were tetA or tetB positive. The prevalence of intI gene was 96%, while only sixteen isolate harboring intII gene (12.5%). Our results showed the high prevalence of integrons in MDR K. pneumoniae, indicating the important role of these genes in the transmission of antibiotic resistance.
Keyphrases
- multidrug resistant
- genome wide
- klebsiella pneumoniae
- genome wide identification
- drug resistant
- copy number
- dna methylation
- gram negative
- acinetobacter baumannii
- genome wide analysis
- bioinformatics analysis
- genetic diversity
- transcription factor
- escherichia coli
- risk factors
- gene expression
- pseudomonas aeruginosa
- single molecule
- label free