Fisetin regulates the biological effects of rat nucleus pulposus mesenchymal stem cells under oxidative stress by sirtuin-1 pathway.

Qing ZhouChao ZhuAnwu XuanJunyou ZhangZhenbiao ZhuLiang TangDike Ruan

Published in: Immunity, inflammation and disease (2023)

-induced apoptosis, inflammation, and ECM degradation by suppressing oxidative stress, this finding may add the theoretical basis for research on new treatment of IDD based on NPMSCs.

Keyphrases

oxidative stress
induced apoptosis
mesenchymal stem cells
diabetic rats
ischemia reperfusion injury
dna damage
endoplasmic reticulum stress
umbilical cord
signaling pathway
stem cells
heat shock
cell therapy
heat stress
replacement therapy