Electrochemical hydrocarboxylation of enol derivatives with CO 2 : access to β-acetoxycarboxylic acids.
Alexander O UstyuzhaninOleg V BityukovPavel V SokolovskiyValentina M MerkulovaAlexey I IlovaiskyLiang-Nian HeVera A Vil'Alexander O Terent EvPublished in: Chemical communications (Cambridge, England) (2024)
Electrochemical hydrocarboxylation of enol acetates with CO 2 is developed. The disclosed process provides β-acetoxycarboxylic acids in 25-66% yields, in contrast to the electrolysis of ketones, silyl enol ethers and vinyl tosylates with CO 2 , which leads mainly to alcohols.