Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma.

Caitlin A Creasy Yuzhong Jeff MengMarie-Andrée ForgetTatiana KarpinetsKatarzyna Tomczak Chip Stewart Carlos A Torres-Cabala Shari A Pilon-ThomasAmod A SarnaikJames J MuleLevi GarrawayMatias A BustosJianhua ZhangSapna Pradyuman PatelAdi DiabIsabella C Glitza Oliva Cassian YeeHussein TawbiMichael K WongJennifer Leigh McQuadeDave S B HoonMichael A DaviesPatrick HwuRodabe N AmariaCara L HaymakerRameen BeroukhimChantale Bernatchez

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Our findings suggest that transcriptional features of melanomas correlate with outcomes after TIL therapy and may provide candidates to guide patient selection.

Keyphrases

case report
gene expression
transcription factor
peripheral blood
mesenchymal stem cells
oxidative stress
bone marrow
replacement therapy