Hydrogen and methane breath test results are negatively associated with IBS and may reflect transit time in post-surgical patients.

Hani Essa Shaheen HamdyDarren GreenSimon Lal John T McLaughlinSandra HoffmannEugena LeitaoPeter Paine

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

Our data suggest that patients with a diagnosis of IBS are statistically less likely to have a positive test and it is of limited utility in this group. Post-surgical patients are more likely to have a positive test, possibly secondary to fast transit rather than bacterial overgrowth, as suggested by a significantly negative association with motility-suppressing drugs in this sub-group.

Keyphrases

irritable bowel syndrome
signaling pathway
electronic health record
biofilm formation
machine learning
artificial intelligence