Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Guoqiang YangJiraporn KantapanMaryam MazharXue BaiYuanxia ZouHonglian WangBingfeng HuangSijing YangNathupakorn DechsupaWang LiPublished in: Stem cell research & therapy (2023)
These data suggested that the combined treatment exerts a collaborative effect in alleviating ICH-induced inflammatory response through the downregulation of the Mincle/syk signaling pathway following ICH, further improving the neurologic deficits and brain edema.
Keyphrases
- signaling pathway
- inflammatory response
- mesenchymal stem cells
- high glucose
- diabetic rats
- pi k akt
- oxidative stress
- tyrosine kinase
- epithelial mesenchymal transition
- cell proliferation
- induced apoptosis
- machine learning
- bone marrow
- quality improvement
- immune response
- lipopolysaccharide induced
- cell therapy
- electronic health record
- lps induced
- deep learning
- blood brain barrier
- combination therapy
- cerebral ischemia