Polymorphisms in eicosanoid-related biosynthesis enzymes associated with acute urticaria/angioedema induced by nonsteroidal anti-inflammatory drug hypersensitivity.

R Jurado-EscobarI DoñaJ R PerkinsJ J LagunaR Muñoz-CanoA García-SánchezP AyusoM J TorresC MayorgaJosé Antonio Cornejo-Garcia

Published in: The British journal of dermatology (2021)

Variants of PTGS1 and ALOX5 may play a role in NIUA and NERD, supporting the proposed mechanisms of NSAID-hypersensitivity and shedding light on their genetic basis.

Keyphrases

drug induced
anti inflammatory
copy number
liver failure
genome wide
adverse drug
angiotensin converting enzyme
respiratory failure
dna methylation
emergency department
intensive care unit
aortic dissection
hepatitis b virus
electronic health record
mechanical ventilation