α-mangostin attenuates pristane-induced lupus nephritis by regulating Th17 differentiation.

Xiaoqing ZhouHuanpeng ChenFengjiao WeiQingyu ZhaoQiao SuYu LeiMeng YinXuyan TianZhonghua LiuBolan YuChuan BaiXixin He Zhaofeng Huang

Published in: International journal of rheumatic diseases (2019)

Thus, α-mangostin demonstrated its potential as a candidate therapeutic drug for LN and other Th17-mediated autoimmune diseases by inhibiting the function of Th17.

Keyphrases

high glucose
diabetic rats
signaling pathway
oxidative stress
adverse drug