Re(I)-Catalyzed Hydropropargylation of Silyl Enol Ethers Utilizing Dynamic Interconversion of Vinylidene-Alkenylmetal Intermediates via 1,5-Hydride Transfer.

Nobuharu IwasawaShoya WatanabeAkane ArioHideyuki Sogo

Published in: Journal of the American Chemical Society (2018)

Re(I)-catalyzed hydropropargylation reaction of silyl enol ethers was realized utilizing dynamic interconversion of vinylidene-alkenylmetal intermediates, where alkenylmetals underwent 1,5-hydride transfer of the α-hydrogen to generate vinylidene intermediates. Furthermore, this process was found to be in an equilibrium.

Keyphrases

room temperature
electron transfer
molecular dynamics
molecular dynamics simulations
aqueous solution