Oncologic and survival outcomes in elderly patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy and total mesorectal excision.
Fang HeMo ChenWei-Wei XiaoQun ZhangYanping LiuJian ZhengXiang-Bo WanYuan-Hong GaoPublished in: Japanese journal of clinical oncology (2021)
For elderly locally advanced rectal cancer patients who have good health and performance status, the addition of neoadjuvant chemotherapy to neoadjuvant chemoradiotherapy and total mesorectal excision can result in disease-related survival rates and oncological outcomes similar to those experienced by younger patients. The decision to use this treatment approach in elderly patients should not be based solely on chronological age.
Keyphrases
- rectal cancer
- locally advanced
- neoadjuvant chemotherapy
- phase ii study
- end stage renal disease
- sentinel lymph node
- ejection fraction
- healthcare
- chronic kidney disease
- newly diagnosed
- mental health
- peritoneal dialysis
- prognostic factors
- prostate cancer
- type diabetes
- risk assessment
- patient reported outcomes
- radiation therapy
- early stage
- middle aged
- metabolic syndrome
- decision making
- climate change
- social media
- clinical trial
- skeletal muscle
- combination therapy