Novel and deleterious nucleotide variations in the HAND1 gene probably affect miRNA target sites and protein function in pediatric patients with congenital heart disease.
Fateme TabriziMehri KhatamiMohammad Mehdi HeidariJosé BragançaHassan TatariMohsen NamnabatMehdi HadadzadehMohammad Ali Navabi ShiraziPublished in: Molecular biology reports (2024)
These findings confirm the phenotypic association between CHDs and HAND1 mutations and can pave the way for developing new preventive and therapeutic strategies.