Induction of SGK1 via glucocorticoid-influenced clinical outcome of triple-negative breast cancer patients.

Junjia ZhangYasuhiro MikiErina IwabuchiJunyao XuAyako KanaiYasuaki SagaraYasuyo OhiYoshiaki RaiRin YamaguchiMaki TanakaTakanori IshidaTakashi SuzukiHironobu Sasano

Published in: Breast cancer research and treatment (2023)

To the best of our knowledge, this is the first study to explore an association between SGK1 and clinicopathological variables and clinical outcome of TNBC patients. SGK1 status was significantly positively correlated with adverse clinical outcome of TNBC patients and promoted carcinoma cell proliferation and migration of carcinoma cells.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
stem cells
mesenchymal stem cells
patient reported
bone marrow